flat profile, moderate signal –> upregulated profile
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variable profile –> bending profile
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bending profile –> variable profile
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peaking profile –> flat profile, moderate signal
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flat profile, moderate signal –> flat profile, low signal
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variable profile –> peaking profile
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flat profile, low signal –> downregulated profile
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flat profile, low signal –> variable profile
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upregulated profile –> flat profile, low signal
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upregulated profile –> variable profile
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