NRF and Frip sample NRF Frip ESCH3K27acX1 0.9969 0.0993 ESCH3K27acX2 0.9989 0.0637 ESCH3K4me3X1 0.9631 0.7420 ESCH3K4me3X2 0.9797 0.6448 NPCH3K27acX1 0.9978 0.0370 NPCH3K27acX2 0.9989 0.0042 NPCH3K4me3X1 0.9960 0.2830 NPCH3K4me3X2 0.9988 0.0606 NeuronH3K27acX1 0.9987 0.0413 NeuronH3K27acX2 0.9991 0.0492 NeuronH3K4me3X1 0.9983 0.1625 NeuronH3K4me3X2 0.9988 0.0839 Jaccard index between replicates ESC 22739 28079 22358 0.785594 H3K4me3 NPC 41616 56301 11232 0.129573 H3K4me3 Neuron 42293 38253 17182 0.271163 H3K4me3 ESC 57689 105874 12333 0.0815513 H3K27ac NPC 16472 4302 799 0.04 H3K27ac Neuron 20983 55428 4669 0.0650804 H3K27ac # of candidate ELSs stage all distal ESC 6245 4899 NPC 365 133 Neuron 2675 1595 # of intronic/intergenic distal ELSs stage distal distal_intronic distal_intergenic ESC 4899 2916 1904 0.595224 0.388651 NPC 133 75 57 0.56391 0.428571 Neuron 1595 972 592 0.609404 0.37116 # of candidate ELSs intersecting with adult tissue-specific ELSs tissue ESC NPC Neuron blood 0 0 0 muscle_smooth 1 0 5 muscle_skeletal_cardiac 8 0 3 brain 32 1 55 fibro_myoblasts 3 0 8 iPS 756 12 21 digestive 1 0 0 mucosa 8 0 1 aorta 5 0 2 common 35 18 52 # of candidate ELSs intersecting with embryo tissue-specific ELSs tissue ESC NPC Neuron differentiated_tissues 10 2 14 neural_progenitors 6 0 6 stem_cells 443 2 5 common 21 5 18 # of adult tissue-specific ELSs intersecting with candidate ELSs tissue ESC NPC Neuron blood 0 0 0 muscle_smooth 1 0 5 muscle_skeletal_cardiac 8 0 3 brain 31 1 56 fibro_myoblasts 3 0 8 iPS 886 12 23 digestive 1 0 0 mucosa 10 0 1 aorta 6 0 2 common 36 19 49 # of embryo tissue-specific ELSs intersecting with candidate ELSs tissue ESC NPC Neuron differentiated_tissues 10 2 12 neural_progenitors 6 0 5 stem_cells 488 2 5 common 16 5 17